PDF Osteoarthritis: A Companion to Rheumatology

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Bills affecting rheumatologists make way to Capitol Hill | MDedge Rheumatology

Image credit: Shutterstock. Researchers have developed a vaccine that blocks the effects of the main cause of pain in osteoarthritis OA - nerve growth factor NGF — in mice.

The researchers developed a virus-like particle vaccine that triggers the immune system to produce antibodies to block naturally-occurring NGF. The new vaccine was tested in mice that had signs of painful OA uneven distribution of weight across the hind legs , and it was shown to visibly reverse these effects. Osteoarthritis is the most common joint disease in humans and is estimated to cost between Professor Martin Bachmann comments: 'I am happy to see the vaccine platform perform so well, and look forward to seeing the vaccine enter clinical testing in companion animals.

Too many people living with pain do not get effective relief from the treatments that are currently available, and that is why the development of more effective pain killers, with fewer side-effects, is vital for people living with arthritis. We are proud to support research such as this, which aims to tackle this urgent problem and discover new ways to help people overcome pain.

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Skip to main content. Vaccine developed to treat osteoarthritic pain.

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